Journal Club: Effect of comorbidity on mortality in multiple sclerosis
نویسندگان
چکیده
منابع مشابه
Journal Club: Effect of comorbidity on mortality in multiple sclerosis.
Multiple sclerosis (MS) is a chronic demyelinating disease of the CNS estimated to reduce life expectancy by 7–14 years compared to demographically similar groups in the general population. While several disease complications pose a potential risk for mortality, results from large observational studies suggest that comorbidities substantially influence survival in MS. In a recent Neurology® art...
متن کاملEffect of comorbidity on mortality in multiple sclerosis
OBJECTIVE We aimed to compare survival in the multiple sclerosis (MS) population with a matched cohort from the general population, and to evaluate the association of comorbidity with survival in both populations. METHODS Using population-based administrative data, we identified 5,797 persons with MS and 28,807 controls matched on sex, year of birth, and region. We estimated annual mortality ...
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Raphael Schneider, MD Nathalie Arbour, PhD The topic of this Journal Club is a study by Bielekova et al.,1 who assessed whether daclizumab monotherapy reduces contrast-enhancing lesions (CEL) in patients with relapsing-remitting multiple sclerosis (RRMS). Furthermore, they evaluated the effects of daclizumab on clinical outcome measures and on NK cell populations in the CSF and blood of treated...
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Multiple sclerosis (MS) is a chronic autoimmune disorder of central nervous system. This demyelinating disease affects more than 2.3 million people world wild. Most of patients are young adult. There are many possible triggering factors including infections, toxin, immunization, trauma, sunlight exposure and hormonal variable in pathogenesis of MS. One of the important trigger is stress. There ...
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ژورنال
عنوان ژورنال: Neurology
سال: 2016
ISSN: 0028-3878,1526-632X
DOI: 10.1212/wnl.0000000000002718